The Humoral Immune Response to BCG Vaccination

The humoral immune response after BCG vaccination in humans: consequences for the serodiagnosis of tuberculosis.

The IgM and IgG response to BCG vaccination was investigated in 75 adults, tuberculin negative before vaccination, using an enzyme-linked immunosorbent assay with purified protein derivative (PPD) as antigen. The mean optical density (OD) increased significantly (p less than 0.001) in both immunoglobulin classes. Increase in at least one class was significant in 89% of the subjects. The observe...

Evaluation of Acute Aflatoxicosis on Humoral Immune Response to Foot-and Mouth Disease Vaccination in Guinea Pigs

Evaluation of Humoral Immune Response to Foot-and-Mouth Disease Vaccination in Experimentally Infected Guinea Pigs with Trypanosoma evansi

Persistence of the immune response induced by BCG vaccination

BACKGROUND Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence concerning the persistence of the BCG vaccine-induced response would help inform decisions about when such boosting would be most effective. M...

Vaccination to gain humoral immune memory

The concept of immune memory forms the biological basis for vaccination programs. Despite advancements in the field of immune memory and vaccination, most current vaccines are evaluated by magnitude of antigen-specific antibody titers in serum or mucosa after vaccination. It has been shown, however, that antibody-mediated humoral immune memory is established regardless of the magnitude and dura...